• Product NameIvabradine hydrochloride
• Brief DescriptionInhibitors
• Purification99.70%
• Biological ActivityIvabradine hydrochloride, a new If inhibitor with IC 50 of 2.9 μM, which is a pure heart rate lowering agent.
• Target NameAdrenergic Receptor inhibitor
• CAS No. 148849-67-6
• Calculated MW 505.05
• Formulation C27H37ClN2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)C[C@H]3CC4=CC(=C(C=C34)OC)OC.Cl
  Pathways:Neuroscience; GPCR/G Protein
  Receptor:Adrenergic Receptor
  Boling pt:
  Melting pt:193-196C
  Solubility:Ethanol: 101 mg/mL (199.98 mM); Water: 82 mg/mL (162.36 mM); DMSO: 101 mg/mL (199.98 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Fang Y, et al. J Cardiovasc Pharmacol, 2012. 59(3): p. 260-7.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting