• Product NamePrucalopride
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityPrucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.
• Target Name5-HT Receptor agonist
• CAS No. 179474-81-8
• Calculated MW 367.87
• Formulation C18H26ClN3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:COCCCN1CCC(CC1)NC(=O)C1=CC(Cl)=C(N)C2=C1OCC2
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT1A; 5-HT1B; 5-HT3; 5-HT4A; 5-HT4B
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 38 mg/mL (103.29 mM); DMSO: 60 mg/mL (163.1 mM)
  Appearance:Transparent Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Briejer MR, et al. Eur J Pharmacol, 2001, 423(1), 71-83.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting