• Product NameLomitapide Mesylate
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityLomitapide Mesylate is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.
• Target NameCETP antagonist
• CAS No. 202914-84-9
• Calculated MW 789.83
• Formulation C40H41F6N3O5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CS(O)(=O)=O.FC(F)(F)CNC(=O)C1(CCCCN2CCC(CC2)NC(=O)C2=CC=CC=C2C2=CC=C(C=C2)C(F)(F)F)C2=CC=CC=C2C2=CC=CC=C12
  Pathways:Metabolism
  Receptor:MTP
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 100 mg/mL (126.6 mM); DMSO: 100 mg/mL (126.6 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Davis KA, Miyares MA. Am J Health Syst Pharm. 2014 Jun 15;71(12):1001-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting