• Product NameAclidinium bromide
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAclidinium Bromide inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.
• Target NameAChR antagonist
• CAS No. 320345-99-1
• Calculated MW 564.55
• Formulation C26H30NO4S2Br
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:C1C[N+]2(CCC1[C@H](C2)OC(=O)C(C3=CC=CS3)(C4=CC=CS4)O)CCCOC5=CC=CC=C5.[Br-]
  Pathways:Neuroscience
  Receptor:M1 mAChR; M2 mAChR; M3 mAChR; M4 mAChR; M5 mAChR
  Boling pt:
  Melting pt:
  Solubility:DMSO: 113 mg/mL (200.15 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sentellas S, et al. Eur J Pharm Sci, 2010, 39(5), 283-290.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting