• Product NameBedaquiline(TMC207; R207910)
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBedaquiline(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.
• Target NameAntibiotic inhibitor
• CAS No. 843663-66-1
• Calculated MW 555.5
• Formulation C32H31BrN2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CN(C)CC[C@@](C1=CC=CC2=CC=CC=C21)([C@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O
  Pathways:Microbiology&virology
  Receptor:Tubercle bacillus
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lakshmanan M, et al. J Young Pharm. 2013 Dec;5(4):112-115.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting