• Product NameVidofludimus(4SC-101; SC12267)
• Brief DescriptionInhibitors
• Purification99.46%
• Biological ActivityVidofludimus (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 value of 134nmol/L for human DHODH.
• Target NameDehydrogenase inhibitor
• CAS No. 717824-30-1
• Calculated MW 355.36
• Formulation C20H18FNO4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:COC1=CC=CC(=C1)C1=CC(F)=C(NC(=O)C2=C(CCC2)C(O)=O)C=C1
  Pathways:Metabolism
  Receptor:Human DHODH
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:Green Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kulkarni OP, et al. Am J Pathol. 2010 Jun;176(6):2840-7.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting