• Product NameCEP-28122
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityCEP-28122 is a highly potent and selective orally active ALK inhibitor with IC50 of 1.9 0.5 nM in an enzyme-based TRF assay.
• Target NameALK inhibitor
• CAS No. 1022958-60-6
• Calculated MW 539.07
• Formulation C28H35ClN6O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:COC1=C(C=CC2=C1CC[C@H](CC2)N3CCOCC3)NC4=NC=C(C(=N4)NC5[C@@H]6C[C@H]([C@@H]5C(=O)N)C=C6)Cl
  Pathways:Angiogenesis; Tyrosine Kinase/Adaptors
  Receptor:ALK
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Abate F, et al. Leukemia. 2015 Jun;29(6):1390-401.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting