• Product NameGSK650394
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityGSK650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor with IC50 of 62 nM and 103 nM for SGK1 and SGK2, respectively.
• Target NameSGK inhibitor
• CAS No. 890842-28-1
• Calculated MW 382.45
• Formulation C25H22N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:OC(=O)C1=C(C=C(C=C1)C1=CNC2=NC=C(C=C12)C1=CC=CC=C1)C1CCCC1
  Pathways:Metabolism
  Receptor:SGK1; SGK2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 76 mg/mL (198.71 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sherk AB, et al. Y Res. 2008, 68(18), 7475-7483.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting