• Product NameUNC2881
• Brief DescriptionInhibitors
• Purification98.97%
• Biological ActivityUNC2881 is a specific Mer tyrosine kinase inhibitor with IC50 of 4.3 nM, about 83- and 58-fold selectivity over Axl and Tyro3, respectively.
• Target NameTAM Receptor inhibitor
• CAS No. 1493764-08-1
• Calculated MW 463.58
• Formulation C25H33N7O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CCCCNC1=NC=C(C(=O)NCC2=CC=C(C=C2)N2C=CN=C2)C(NC2CCC(O)CC2)=N1
  Pathways:Tyrosine Kinase/Adaptors
  Receptor:AXL; Mer; Tyro3
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 5 mg/mL warmed (10.78 mM); DMSO: 92 mg/mL (198.45 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zhang W, et al. J Med Chem. 2013, 56(23), 9693-9700.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting