• Product NameMI-3 (Menin-MLL Inhibitor)
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityMI-3 (Menin-MLL Inhibitor) is a potent menin-MLL interaction inhibitor with IC50 of 648 nM.
• Target NameHistone Methyltransferase inhibitor
• CAS No. 1271738-59-0
• Calculated MW 375.55
• Formulation C18H25N5S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC(C)C1=NC(N2CCN(CC2)C2=NCC(C)(C)S2)=C2C=CSC2=N1
  Pathways:Chromatin/Epigenetic
  Receptor:Menin-MLL
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 19 mg/mL warmed (50.59 mM); DMSO: 19 mg/mL warmed (50.59 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Grembecka J, et al. Nat Chem Biol. 2012, 8(3), 277-284.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting