• Product NameFK866 (APO866, Daporinad)
• Brief DescriptionInhibitors
• Purification99.96%
• Biological ActivityFK866 (APO866, Daporinad) effectively inhibits nicotinamide phosphoribosyltransferase (NMPRTase) with IC50 of 0.09 nM in a cell-free assay. Phase 1/2.
• Target NameTransferase inhibitor
• CAS No. 658084-64-1
• Calculated MW 391.51
• Formulation C24H29N3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:C1CN(CCC1CCCCNC(=O)/C=C/C2=CN=CC=C2)C(=O)C3=CC=CC=C3
  Pathways:Metabolism
  Receptor:NMPRTase
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 78 mg/mL (199.22 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Nahimana A, et al. Blood, 2009, 113(14), 3276-3286.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting