• Product NameVilanterol (GW642444; GW 642444X)
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityVilanterol (GW642444; GW 642444X) is a novel, inhaled, long-acting β(2) agonist with inherent 24-h activity under development as a once-daily combination therapy with an inhaled corticosteroid for COPD and asthma.
• Target NameAdrenergic Receptor agonist
• CAS No. 503068-34-6
• Calculated MW 486.43
• Formulation C24H33Cl2NO5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:C1=CC(=C(C(=C1)Cl)COCCOCCCCCCNC[C@@H](C2=CC(=C(C=C2)O)CO)O)Cl
  Pathways:GPCR/G Protein
  Receptor:β1-adrenoceptor; β2-adrenoceptor; β3-adrenoceptor
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Slack RJ, et al. J Pharmacol Exp Ther. 2013 Jan;344(1):218-30

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting