• Product NameINCB024360 analogue
• Brief DescriptionInhibitors
• Purification98.71%
• Biological ActivityIDO-IN-2 is a potent IDO1 inhibitor(IC50=10 nM) with desirable pharmaceutical properties, which is poised to start clinical trials in Y patients.
• Target NameIDO inhibitor
• CAS No. 914471-09-3
• Calculated MW 271.64
• Formulation C9H7ClFN5O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:C1=CC(=C(C=C1N/C(=C\2/C(=NON2)N)/N=O)Cl)F
  Pathways:Metabolism
  Receptor:IDO1
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 54 mg/mL warmed (198.79 mM); DMSO: 54 mg/mL warmed (198.79 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yue EW, et al. J Med Chem. 2009, 52(23), 7364-7367.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting