• Product NamePimecrolimus
• Brief DescriptionInhibitors
• Purification95.00%
• Biological ActivityPimecrolimus, like all ascomycins, is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12.
• Target NameOthers
• CAS No. 137071-32-0
• Calculated MW 810.45
• Formulation C43H68ClNO11
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC[C@@H]1/C=C(/C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@@H]([C@@H](C4)OC)Cl)/C)O)C)OC)OC)C)\C
  Pathways:Others
  Receptor:Others
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 100 mg/mL (123.38 mM); DMSO: 100 mg/mL (123.38 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Nghiem P, et al. Am Acad Dermatol, 2002, 46(2), 228-241.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting