• Product NameBAY85-3934;Molidustat
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityMolidustat(BAY-85-3934) is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells; HIF-stabilizer.
• Target NameHIF/HIF Prolyl-Hydroxylase inhibitor
• CAS No. 1154028-82-6
• Calculated MW 314.3
• Formulation C13H14N8O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:O=C1N(NC=C1N1C=CN=N1)C1=CC(=NC=N1)N1CCOCC1
  Pathways:Metabolism; Chromatin/Epigenetic
  Receptor:PHD1; PHD2; PHD3
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Flamme I, et al. PLoS One. 2014 Nov 13;9(11):e111838.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting