• Product NameFruquintinib
• Brief DescriptionInhibitors
• Purification99.89%
• Biological ActivityFruquintinib (HMPL-013) is a small molecule vascular endothelial growth factor receptors inhibitor.
• Target NameVEGFR inhibitor
• CAS No. 1194506-26-7
• Calculated MW 393.39
• Formulation C21H19N3O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CNC(=O)C1=C(C)OC2=C1C=CC(OC1=NC=NC3=CC(OC)=C(OC)C=C13)=C2
  Pathways:Angiogenesis; Tyrosine Kinase/Adaptors
  Receptor:VEGFR
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Gu Y, et al. Y ChemOthers Pharmacol. 2014 Jul;74(1):95-115.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting