• Product NameOC000459
• Brief DescriptionInhibitors
• Purification99.51%
• Biological ActivityOC000459 is a potent and selective D prostanoid receptor 2 (DP2) antagonist with IC50 of 13 nM. Phase 2.
• Target NameGPR antagonist
• CAS No. 851723-84-7
• Calculated MW 348.37
• Formulation C21H17FN2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CC1=C(CC2=NC3=CC=CC=C3C=C2)C2=C(C=CC(F)=C2)N1CC(O)=O
  Pathways:Endocrinology/Hormones
  Receptor:DP2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 4 mg/mL (11.48 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Pettipher R, et al. J Pharmacol Exp Ther, 2012, 340(2), 473-482.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting