• Product Name4EGI-1
• Brief DescriptionInhibitors
• Purification95.78%
• Biological Activity4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM.
• Target NamePERK inhibitor
• CAS No. 315706-13-9
• Calculated MW 451.28
• Formulation C18H12Cl2N4O4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:C1=CC=C(C(=C1)C/C(=N\NC2=NC(=CS2)C3=CC(=C(C=C3)Cl)Cl)/C(=O)O)[N+](=O)[O-]
  Pathways:Apoptosis
  Receptor:eIF-4E/eIF-4G
  Boling pt:
  Melting pt:
  Solubility:DMSO: 90 mg/mL (199.43 mM)
  Appearance:Taupe Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Moerke NJ, et al. Cell. 2007, 128(2), 257-267.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting