• Product NameVE822
• Brief DescriptionInhibitors
• Purification99.70%
• Biological ActivityVE-822 is an ATR inhibitor with IC50 of 19 nM in HT29 cells
• Target NameATM/ATR inhibitor
• CAS No. 1232416-25-9
• Calculated MW 463.55
• Formulation C24H25N5O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CNCC1=CC=C(C=C1)C1=NOC(=C1)C1=NC(=CN=C1N)C1=CC=C(C=C1)S(=O)(=O)C(C)C
  Pathways:DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
  Receptor:ATM; ATR
  Boling pt:
  Melting pt:
  Solubility:DMSO: 36 mg/mL (77.66 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Fokas E, et al. Cell Death Dis, 2012, 3, e441.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting