• Product NameA-438079 hydrochloride
• Brief DescriptionInhibitors
• Purification99.74%
• Biological ActivityA-438079 hydrochloride is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.
• Target NameP2 Receptor antagonist
• CAS No. 899431-18-6
• Calculated MW 342.61
• Formulation C13H10Cl3N5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.ClC1=CC=CC(C2=NN=NN2CC2=CN=CC=C2)=C1Cl
  Pathways:Neuroscience
  Receptor:P2X7
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 20 mg/mL warmed (58.37 mM); Water: 61 mg/mL (178.04 mM); DMSO: 61 mg/mL (178.04 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. McGaraughty S, et al. Neuroscience. 2007, 146(4), 1817-1828.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting