• Product NameLB42708
• Brief DescriptionInhibitors
• Purification99.06%
• Biological ActivityLB42708 is an orally active farnesyltransferase (FTase) inhibitor with IC50 of 0.8, 1.2, and 2.0 nM toward H-ras, N-ras, and K-ras, respectively.
• Target NameTransferase inhibitor
• CAS No. 226929-39-1
• Calculated MW 555.46
• Formulation C30H27BrN4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:BrC1=CC=C(CN2C=NC=C2CN2C=C(C(=O)N3CCOCC3)C(=C2)C2=CC=CC3=CC=CC=C23)C=C1
  Pathways:Metabolism
  Receptor:Farnesyl transferase (FTase); Farnesyl transferase (FTase); Farnesyl transferase (FTase)
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 86 mg/mL warmed (154.82 mM); DMSO: 100 mg/mL (180.03 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Na HJ, et al. J Immunol. 2004, 173(2), 1276-1283.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting