• Product NamehPGDS-IN-1
• Brief DescriptionInhibitors
• Purification99.43%
• Biological ActivityhPGDS-IN-1 is a hPGDS inhibitor ,with IC50 of 12 nM in the Fluorescence Polarization Assay or the EIA assay.
• Target NamePGE Synthase inhibitor
• CAS No. 1234708-04-3
• Calculated MW 416.43
• Formulation C22H20N6O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC(C)(O)C1=NC(=NO1)C1=CC(CNC(=O)C2=CN=C(N=C2)C2=CC=CC=N2)=CC=C1
  Pathways:Immunology/Inflammation
  Receptor:hPGDS
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Vandeusen, et al. From PCT Int. Appl. (2011), WO 2011044307 A1 20110414.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting