• Product NameAcalisib (GS-9820)
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityAcalisib (GS-9820) is a potent and selective inhibitor of PI3Kδ with IC50 value of 12.7 nM
• Target NamePI3K inhibitor
• CAS No. 870281-34-8
• Calculated MW 401.4
• Formulation C21H16FN7O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C[C@@H](C1=NC2=C(C=C(C=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:PI3Kδ
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shugg RP, et al. J Biol Chem. 2013 Dec 6;288(49):35346-57.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting