• Product NameAG1024
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityAG-1024 (Tyrphostin) inhibits IGF-1R autophosphorylation with IC50 of 7 μM, less potent to IR with IC50 of 57 μM.
• Target NameIGF-1R inhibitor
• CAS No. 65678-07-1
• Calculated MW 305.17
• Formulation C14H13BrN2O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(C)(C)C1=C(C(=CC(=C1)C=C(C#N)C#N)Br)O
  Pathways:Tyrosine Kinase/Adaptors
  Receptor:IGF-1R; Insulin Receptor
  Boling pt:
  Melting pt:
  Solubility:DMSO: 61 mg/mL (199.88 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. von Willebrand M, et al. Y Res, 2003, 63(6), 1420-1429.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting