• Product NameMLN0905
• Brief DescriptionInhibitors
• Purification99.38%
• Biological ActivityMLN0905 is a potent inhibitor of PLK1 with IC50 of 2 nM.
• Target NamePLK inhibitor
• CAS No. 1228960-69-7
• Calculated MW 486.56
• Formulation C24H25F3N6S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CN(C)CCCC1=CC(NC2=NC=C3CC(=S)NC4=C(C=CC(=C4)C(F)(F)F)C3=N2)=C(C)N=C1
  Pathways:Cell Cycle/Checkpoint
  Receptor:PLK1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 97 mg/mL (199.35 mM)
  Appearance:Gray Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Duffey MO, et al. J Med Chem, 2012, 55(1), 197-208.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting