• Product NameMutant EGFR inhibitor
• Brief DescriptionInhibitors
• Purification97.70%
• Biological ActivityMutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor(L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant).
• Target NameEGFR inhibitor
• CAS No. 1421373-62-7
• Calculated MW 520.03
• Formulation C27H30ClN7O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:COC1=C(NC2=NC=C(Cl)C(=N2)C2=CNC3=CC=CC=C23)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C
  Pathways:Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
  Receptor:EGFR (mutant)
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

N/A

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting