• Product NamePifithrin-α
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityPifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes.
• Target Namep53 inhibitor
• CAS No. 63208-82-2
• Calculated MW 367.3
• Formulation C16H18N2OSHBr
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:Br.CC1=CC=C(C=C1)C(=O)CN1C(=N)SC2=C1CCCC2
  Pathways:Apoptosis
  Receptor:p53
  Boling pt:
  Melting pt:
  Solubility:DMSO: 67 mg/mL (182.41 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Komarov PG, et al. Science, 1999, 285(5434), 1733-1737.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting