• Product NameTCS 1102
• Brief DescriptionInhibitors
• Purification97.28%
• Biological ActivityTCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively).
• Target NameOX Receptor antagonist
• CAS No. 916141-36-1
• Calculated MW 470.59
• Formulation C27H26N4O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CN1C2=CC=CC=C2N=C1SCC(=O)N3CCC[C@H]3C(=O)NC4=CC=CC=C4C5=CC=CC=C5
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:OX1; OX2
  Boling pt:
  Melting pt:
  Solubility:DMSO, Ethanol: 100 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Bergman JM, et al. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1425-30.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting