• Product NameTCS 5861528
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityTCS5861528 is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx (IC50 values are 14.3 and 18.7μM respectively).
• Target NameTRP/TRPV Channel inhibitor
• CAS No. 332117-28-9
• Calculated MW 369.42
• Formulation C19H23N5O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCC(C)C1=CC=C(NC(=O)CN2C=NC3=C2C(=O)N(C)C(=O)N3C)C=C1
  Pathways:Membrane transporter/Ion channel
  Receptor:TRPA1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 100 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wei H, et al. Anesthesiology. 2009 Jul;111(1):147-54.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting