• Product NameIlomastat (GM6001, Galardin)
• Brief DescriptionInhibitors
• Purification99.51%
• Biological ActivityIlomastat (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-14, and MMP-26 with Ki of 0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM, 0.36 nM, respectively.
• Target NameMMP inhibitor
• CAS No. 142880-36-2
• Calculated MW 388.46
• Formulation C20H28N4O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC
  Pathways:Proteases/Proteasome
  Receptor:MMP-1; MMP-12; MMP-2; MMP-26; MMP-7; MMP-8; MMP-9
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 8 mg/mL (20.59 mM); DMSO: 78 mg/mL (200.79 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Grobelny D, et al. Biochemistry, 1992, 31(31), 7152-714.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting