• Product NameRubescensin A
• Brief DescriptionInhibitors
• Purification94.25%
• Biological ActivityOridonin has potent anti-tumor activity. Oridonin targets AE (AML1-ETO) oncoprotein. Exposure to oridonin induces apoptosis in AE-bearing leukemic cells through the activation of intrinsic apoptotic pathway and triggering a caspase-3-mediated degradation
• Target NameOthers
• CAS No. 28957-04-2
• Calculated MW 364.44
• Formulation C20H28O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1(C)CCC(O)C23COC(O)(C(O)C12)C12C(O)C(CCC31)C(=C)C2=O
  Pathways:Others
  Receptor:Others
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 28 mg/mL (76.83 mM); DMSO: 73 mg/mL (200.31 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ikezoe T, et al. Int J Oncol, 2003, 23(4), 1187-1193.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting