• Product NameCryptotanshinone
• Brief DescriptionInhibitors
• Purification98.91%
• Biological ActivityCryptotanshinone is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5.
• Target NameSTAT inhibitor
• CAS No. 35825-57-1
• Calculated MW 296.37
• Formulation C19H20O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C[C@H]1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C
  Pathways:JAK/STAT signaling; Stem Cells
  Receptor:STAT3
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 1 mg/mL warmed (3.37 mM); DMSO: 5 mg/mL warmed (16.87 mM)
  Appearance:Red Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shin DS, et al. Y Res, 2009, 69(1), 193-202.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting