• Product Name(+)-Bicuculline
• Brief DescriptionInhibitors
• Purification99.59%
• Biological ActivityBicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.
• Target NameGABA Receptor antagonist
• CAS No. 485-49-4
• Calculated MW 367.36
• Formulation C20H17NO6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3
  Pathways:Membrane transporter/Ion channel; Neuroscience
  Receptor:GABAR
  Boling pt:
  Melting pt:
  Solubility:DMSO: 73 mg/mL warmed (198.72 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Huang SH, et al. Eur J Pharmacol, 2003, 464(1), 1-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting