• Product NameHonokiol
• Brief DescriptionInhibitors
• Purification99.65%
• Biological ActivityHonokiol is the active principle of magnolia extract that inhibits Akt-phosphorylation and promotes ERK1/2 phosphorylation.
• Target NameAkt inhibitor; MEK inhibitor
• CAS No. 35354-74-6
• Calculated MW 266.32
• Formulation C18H18O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:OC1=C(CC=C)C=C(C=C1)C1=C(O)C=CC(CC=C)=C1
  Pathways:Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
  Receptor:P-Akt; MEK
  Boling pt:
  Melting pt:
  Solubility:DMSO: 53 mg/mL (198.99 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Seo MS, et al. Toxicol Appl Pharmacol. 2015 Apr 15;284(2):113-24.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting