• Product NameCelastrol
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCelastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM.
• Target NameProteasome inhibitor
• CAS No. 34157-83-0
• Calculated MW 450.62
• Formulation C29H38O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC1=C(C(=O)C=C2C1=CC=C3[C@]2(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4C[C@](CC5)(C)C(=O)O)C)C)C)C)O
  Pathways:Proteases/Proteasome; Ubiquitination
  Receptor:20S proteasome
  Boling pt:
  Melting pt:
  Solubility:DMSO: 90 mg/mL (199.72 mM)
  Appearance:Orange Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yang H, et al. Y Res, 2006, 66(9), 4758-4765.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting