• Product NameCyclizine dihydrochloride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCyclizine 2hydrochloride is a histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness.
• Target NameHistamine Receptor antagonist
• CAS No. 5897-18-7
• Calculated MW 339.3
• Formulation C18H24Cl2N2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.Cl.CN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:H1 receptor
  Boling pt:
  Melting pt:
  Solubility:Water: 68 mg/mL (200.41 mM); DMSO: 7 mg/mL (20.63 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Vella-Brincat JW, et al. J Pain Symptom Manage. 2012 Mar;43(3):540-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting