• Product NameSalubrinal
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivitySalubrinal is a selective inhibitor of eukaryotic translation initiation factor 2 subunit α (eIF2α) dephosphorylation.
• Target NamePERK inhibitor
• CAS No. 405060-95-9
• Calculated MW 479.81
• Formulation C21H17Cl3N4OS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:C1=CC=C(C=C1)/C=C/C(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC2=CC=CC3=C2N=CC=C3
  Pathways:Apoptosis
  Receptor:eIF-2α
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 2 mg/mL (4.16 mM); DMSO: 96 mg/mL (200.07 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yuta Komoike, et al. Archives of Toxicology.2012, 86(1): 37-44.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting