• Product NameBMY 7378 dihydrochloride
• Brief DescriptionInhibitors
• Purification99.08%
• Biological ActivityBMY-7,378 is a 5-HT1A receptor weak partial agonist/antagonist and α1D-adrenergic receptor antagonist.
• Target Name5-HT Receptor antagonist; Adrenergic Receptor antagonist; Dopamine Receptor inhibitor
• CAS No. 21102-95-4
• Calculated MW 458.42
• Formulation C22H33Cl2N3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.Cl.COC1=CC=CC=C1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT1A; 5-HT1C; α1D-adrenoceptor; α2C-adrenoceptor; D2
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 20 mg/mL (43.62 mM); Water: 92 mg/mL (200.68 mM); DMSO: 92 mg/mL (200.68 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Cleary L, et al. Auton Autacoid Pharmacol. 2005 Oct;25(4):135-41.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting