• Product NameML-7 hydrochloride
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityML-7 Hcl is a cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM); also inhibt smooth-muscle myosin light chain kinase, protein kinase C (PKC) and cAMP-dependent protein kinase (PKA).
• Target NamePKA inhibitor; PKC inhibitor; Serine/threonin kinase inhibitor
• CAS No. 110448-33-4
• Calculated MW 452.74
• Formulation C15H18ClIN2O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3I.Cl
  Pathways:Apoptosis; Cytoskeletal Signaling; GPCR/G Protein
  Receptor:PKA; PKC; MLCK
  Boling pt:
  Melting pt:
  Solubility:DMSO: >43 mg/mL
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Luh Clara, et al. Journal of Neurochemistry (2010), 112(4), 1015-1025.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting