- Product NamePF06463922
- Brief DescriptionInhibitors
- Purification99.50%
- Biological ActivityPF-06463922 is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively. Phase 1.
- Target NameALK inhibitor; ROS inhibitor; Tyrosine Kinases inhibitor
- CAS No. 1454846-35-5
- Calculated MW 406.41
- Formulation C21H19FN6O2
- Storage 3 years -20˚C powder;2 years -80˚C in solvent;