• Product NameWIKI4
• Brief DescriptionInhibitors
• Purification99.69%
• Biological ActivityWIKI4 is a novel Tankyrase inhibitor with IC50 of 15 nM for TNKS2, and leads to inhibition of Wnt/beta-catenin signaling.
• Target NamePPAR inhibitor
• CAS No. 838818-26-1
• Calculated MW 521.59
• Formulation C29H23N5O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:COC1=CC=C(C=C1)N1C(SCCCN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O)=NN=C1C1=CC=NC=C1
  Pathways:Metabolism
  Receptor:TNKS2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 7 mg/mL;Water: <1 mg/mL
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. James RG, et al. PLoS One. 2012, 7(12), e50457.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting