• Product NamePF670462
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityPF-670462 is a potent (IC50 = 7.7 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.
• Target NameCasein Kinase inhibitor
• CAS No. 950912-80-8
• Calculated MW 410.32
• Formulation C19H22Cl2FN5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:Cl.Cl.NC1=NC=CC(=N1)C1=C(N=CN1C1CCCCC1)C1=CC=C(F)C=C1
  Pathways:Metabolism; Stem Cells
  Receptor:CK1ε
  Boling pt:
  Melting pt:
  Solubility:DMSO, Ethanol: 200 mM
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Daniel I Perez, et al. Med Res Rev.2011,31(6): 924-954.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting