• Product NameSB216763
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivitySB216763 is a potent and selective GSK-3 inhibitor with IC50 of 34.3 nM for GSK-3α and equally effective at inhibiting human GSK-3β.
• Target NameGSK-3 inhibitor
• CAS No. 280744-09-4
• Calculated MW 371.22
• Formulation C19H12N2O2Cl2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CN1C=C(C2=CC=CC=C12)C1=C(C(=O)NC1=O)C1=C(Cl)C=C(Cl)C=C1
  Pathways:PI3K/Akt/mTOR signaling; Stem Cells
  Receptor:GSK-3α; GSK-3β
  Boling pt:
  Melting pt:
  Solubility:DMSO: 23 mg/mL (61.95 mM)
  Appearance:Red Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Coghlan MP, et al. Chem Biol, 2000, 7(10), 793-803.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting