- Product NamePyridone 6
- Brief DescriptionInhibitors
- Purification98.74%
- Biological ActivityPyridone 6(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM) for other protein tyrosine kinases.
- Target NameJAK inhibitor; Tyrosine Kinases inhibitor
- CAS No. 457081-03-7
- Calculated MW 309.34
- Formulation C18H16FN3O
- Storage 3 years -20˚C powder;2 years -80˚C in solvent;
