• Product NameSGC707
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySGC707 is a first-in-class PRMT3 chemical probe which is a potent, selective, and cell-active allosteric inhibitor of PRMT3 with IC50 of 31 nM.
• Target NameHistone Methyltransferase inhibitor
• CAS No. 1687736-54-4
• Calculated MW 298.34
• Formulation C16H18N4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1CCN(C1)C(=O)CNC(=O)NC2=CC3=C(C=C2)C=NC=C3
  Pathways:Chromatin/Epigenetic
  Receptor:PRMT3; PRMT3
  Boling pt:
  Melting pt:
  Solubility:DMSO, Ethanol: 59 mg/mL (197.76 mM)
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kaniskan H?, et al. Angew Chem Int Ed Engl. 2015, 54(17), 5166-5170.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting