• Product NamePS-1145
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityPS-1145 is a specific?IKK?inhibitor with?IC50?of 88 nM.
• Target NameIκB/IKK inhibitor
• CAS No. 431898-65-6
• Calculated MW 322.75
• Formulation C17H11ClN4O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer/ respiratory system/ Cardiovascular/ Metabolism
  SMILES:C1=CC(=CN=C1)C(=O)NC2=C3C(=CC(=C2)Cl)C4=C(N3)C=NC=C4
  Pathways:NF-κb
  Receptor:IKK
  Boling pt:
  Melting pt:
  Solubility:DMSO: 64 mg/mL (198.29 mM); Ethanol: 2 mg/mL warming (6.19 mM)
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hideshima T, et al. J Biol Chem. 2002, 277(19), 16639-16647.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting