• Product NameVorapaxar sulfate
• Brief DescriptionInhibitors
• Purification99.46%
• Biological ActivityVorapaxar (SCH 530348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.
• Target NameProtease-activated Receptor inhibitor
• CAS No. 705260-08-8
• Calculated MW 590.66
• Formulation C29H35FN2O8S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CCOC(=O)N[C@@H]1CC[C@@H]2[C@@H](C1)C[C@@H]3[C@H]([C@H]2/C=C/C4=NC=C(C=C4)C5=CC(=CC=C5)F)[C@H](OC3=O)C.OS(=O)(=O)O
  Pathways:GPCR/G Protein
  Receptor:PAR-1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 99 mg/mL;Ethanol: 99 mg/mL
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Chackalamannil S, et al. J Med Chem, 2008, 51(11), 3061-3064.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting