• Product NameNQDI-1
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivitySelective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50?= 3?μM, Ki?= 500 nM)
• Target NameASK inhibitor; MAPK inhibitor
• CAS No. 175026-96-7
• Calculated MW 319.31
• Formulation C19H13NO4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CCOC(=O)C1=C2C3=CC=CC=C3C(=O)C4=C2C(=CC=C4)NC1=O
  Pathways:Apoptosis; MAPK
  Receptor:ASK1; MAP3K5
  Boling pt:
  Melting pt:
  Solubility:DMSO: 21 mg/mL (65.76 mM)
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Volynets GP, et al.J Med Chem. 2011 Apr 28;54(8):2680-6.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting