• Product NameL67
• Brief DescriptionInhibitors
• Purification97.00%
• Biological ActivityL67 is a novel, competitive human DNA ligase inhibitor, inhibits DNA ligases I and III with IC50 of 10 μM and 10 μM.
• Target NameDNA inhibitor
• CAS No. 325970-71-6
• Calculated MW 486.11
• Formulation C16H14Br2N4O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC1=C(C=C(C=C1Br)NCC(=O)NN/C=C\2/C=C(C=CC2=O)[N+](=O)[O-])Br
  Pathways:DNA Damage/DNA Repair
  Receptor:DNA ligases
  Boling pt:
  Melting pt:
  Solubility:DMSO: > 10 mM
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Chen X, et al. Y Res. 2008 May 1;68(9):3169-3177.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting