• Product NameC-DIM12
• Brief DescriptionInhibitors
• Purification95.00%
• Biological ActivityC-DIM12 induced expression of Nurr1-regulated genes that was abolished by Nurr1 knockdown. C-DIM12 increased expression of transfected human Nurr1, induced Nurr1 protein expression in primary dopaminergic neurons and enhanced neuronal survival from exposure to 6-OHDA.
• Target NameOthers
• CAS No. 178946-89-9
• Calculated MW 356.85
• Formulation C23H17ClN2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous System
  SMILES:ClC1=CC=C(C=C1)C(C1=CNC2=CC=CC=C12)C1=CNC2=CC=CC=C12
  Pathways:Others
  Receptor:Nurr1 activator
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:Pink powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hammond SL, Safe S, Tjalkens RB. Neurosci Lett. 2015 Oct 21;607:83-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting